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Surgery for Breast Cancer 

Surgery is a very common treatment for breast cancer, as it is almost always an option for every stage of breast cancer except stage 4. 

 

Objectives of Surgery 

There are two main objectives of surgery: 

1) Remove the cancer from the breast 

2) Evaluate the Lymph Nodes    

     -helps with cancer staging        

    -Local Control (removing the lymph nodes with cancer in order to prevent local recurrence and learn more about it). 

 

 

                      

 Types of Breast Cancer Surgery 

There are two main types of breast cancer surgery: A mastectomy, which involves the removal of the entirety of one or both breasts, and a lumpectomy (or partial mastectomy), which involves the removal of only the part of the breast in which the cancer cells live. 

 Mastectomy 


A mastectomy is a breast cancer surgery in which the entire breast is removed. You may need a total mastectomy if you have inflammatory breast cancer, an inability to undergo radiation therapy, multicentricity (more than one cancer in more than one quadrant of the breast), or an abnormally large tumor. There are multiple types of mastectomies. 
 

1) Conventional Mastectomy 
A Conventional Mastectomy involves removing the entire breast, including the nipple and the skin. Surgeons may also perform a sentinel node biopsy, and remove a few axillary lymph nodes. Although a mastectomy will leave you flat, reconstructive surgery will most likely be an option in the future.
Who can get simple mastectomy? 
-women with breast cancer with micrometastesis (.2-2mm of cancer) in the sentinel lymph nodes 
-women with DCIS or LCIS
-patient preference (peace of mind, etc.) 
-those who cannot have breast conserving surgery due to their inability to undergo radiation therapy (previous radiation therapy, collagen vascular disorders, etc). 


2) Modified Radical Mastectomy 
A modified radical mastectomy includes the removal of the breast tissue, the nipple and areola, the skin, and the axillary lymph nodes, which are the lymph nodes in the armpit (this is called an axillary lymph node dissection, or ALND). 
Who should have a MRM? 

This surgery is common for those with inflammatory breast cancer.  An MRM may also be performed if your breast cancer has spread to multiple lymph nodes, in order to remove the cancer in the breast and in the lymph nodes at the same time. 


3) Radical Mastectomy 
A radical mastectomy is a surgery in which the breast tissue, nipple and areola, the skin, the axillary lymph nodes, AND the pectoralis (chest) muscles are removed.
Who should have a Radical Mastectomy? 
This type of surgery is usually only performed if the tumor is growing into the muscles of the chest. Although it used to be the standard of treatment, it is now very rare, as it has a similar survival outcome to a modified radical mastectomy, which is much less invasive. 


4) Skin Sparing Mastectomy 
A skin sparing mastectomy is a procedure in which the breast tissue, the nipple, and the areola are removed, but the skin around the breast is left in place. This surgery also involves immediate reconstruction, either with an implant or with autologous reconstruction (in which your own muscle, fat, and/or skin will be used to reconstruct the breast). 
Who can have a SSM? 
An SSM is NOT a possible treatment option for those with inflammatory breast cancer (because it involves the skin), and will most likely not be possible for those with tumors close to the skin or very large tumors. However, this surgery is most likely a possibility for most other women, and is advantageous because it involves less scar tissue and looks very natural. 


5) Nipple Sparing Mastectomy 
A nipple sparing mastectomy is a surgery in which the breast tissue is removed, but the skin, nipple, and areola are left behind. During this surgery, the surgeon will test the breast tissue behind your nipple for cancer; if it is positive, the nipple and aerola must be taken out.
Who can have a NSM? 
To assess if you can have an NSM, your doctor will consider the extent of your cancer and the proximity of the cancer to the nipple. For example, those with a small, early stage cancer far away from the nipple will most likely qualify for an NSM. However, those who have Paget's Disease (cancer in the nipple), ptosisor large tumors will most likely be ineligible. 

6) Contralateral Prophylactic (Double) Mastectomy 
A double mastectomy involves the removal of both breasts.
Who should have a double mastectomy? 
-
Those with cancer in both breasts
-Some women with cancer in one breast:
Women who have unilateral breast cancer (cancer in one breast) have a 0.5-1% risk per year of developing breast cancer in the other breast. Although this may seem like an insignificant number, if a 30 year old is diagnosed with unilateral breast cancer, by the time they turn 80, that risk will have increased to 25-50%.  A prophylactic mastectomy will reduce that risk by 95%. Therefore, younger women diagnosed with unilateral breast cancer may consider a CPM to reduce their risk of cancer in their other breast in the future. 
-Women with high risk mutations: 
Women with a very high risk for breast cancer, due to a mutation such as BCRA 1 or 2 may also choose to have a double mastectomy.
-peace of mind
-ease in follow up for those with history of unilateral cancer (less frequent surveillance) 

Lumpectomy/Partial Mastectomy 

A lumpectomy, or breast-conserving surgery, is a surgery in which only the cancer and a margin (a rim of healthy tissue around the cancer) is removed from the breast, in order to conserve as much of the breast as possible. Some lymph nodes may also be removed during this surgery. This surgery is almost always accompanied by radiation therapy, in order to lower the risk of cancer recurrence. 

Who can/can't have a lumpectomy? 
You usually CANNOT have a lumpectomy if:
-you have inflammatory breast cancer
-you are unable or unwilling to receive radiation therapy due to previous radiation therapy, collagen vascular disorders, etc.
-your cancer is multicentric (more than one tumor in more than one quadrant of the breast) 
-your tumor is larger than 5cm 
-you are at very high risk for a second cancer (eg. if you have genetic mutations such as BCRA or ATM).
In these cases, you will most likely need a mastectomy.
Most other women will qualify for a lumpectomy. 


Advantages of a Lumpectomy: 
-usually a day surgery (no need to stay overnight in the hospital). 
-quick recovery time (about 2 weeks)
-conserves most of your breast (in most cases) 
Disadvantages of a Lumpectomy 
-you will most likely need radiation therapy 
-possible cosmetic assymetry
-side effects are possible: 
       -swelling of the breast 
       -pain and tenderness
       -Post Mastectomy Pain Syndrome (nerve pain in chest wall, upper arm, and/or axilla) 
       -if you also have an axillary lymph node dissection, lymphedema is a possibility. Lymphedema is tissue swelling (edema) due to blockage in the lymphatic system (due to lymph node surgery) that prevents the drainage of protein-rich fluid. This condition can lead to a decreased range of motion in the affected arm, along with an increased risk of sepsis and skin infections. However, this condition is treatable. Furthermore, exercise is a very effective way to reduce your risk of lymphedema; 22% of patients experience some form of lymphedema, but only 7% of patients who exercise experience lymphedema.  

How do I know if my lumpectomy removed all of my cancer? 
After your lumpectomy, a pathologist will test the margins that were removed for cancer . If the margins test negative, this means that all of the cancer was removed. However, if the margins are positive, you will most likely need to have a second surgery called a re-excision. If the margins are still positive after the re-excision, a mastectomy may be necessary.  

References: Yale Online. (2016). Introduction to Breast Cancer. https://online.yale.edu/courses/introduction-breast-cancer
American Cancer Society. (2023).  Surgery for Breast Cancer.  Retrieved from: https://www.cancer.org/cancer/types/breast-cancer/treatment/surgery-for-breast-cancer.html
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